The timely
control of a sequence of several different perfusion solutions to a preparation
can be a very difficult task. Manually handling stopcocks can cause unwanted
electrical artifacts and vibrations. The PS1 is a programmable system
that allows unattended solution switching. Stopcocks are replaced by solenoid
valves to avoid vibrations during solution changes and the use of low
noise circuitry prevents interference in the recordings.
- Unattended
solution switching
- Increased reproducibility
- Manual and external
valve control
Valve switching
is accurate to 0.01 seconds with programs up to 99 hours long under
microprocessor control. Consistent liquid delivery means better data.
Choose between speed, cost, and ease of cleaning. Several options are
available for fittings and reservoirs. Flexible design, easy cleaning
and calibration. Slave mode valve operation controlled by your computer,
using available programs.
Perfusion systems
include controller, valves, 140 ml syringe reservoirs and drippers (or
35 ml syringes and 2-way stopcocks in Luer-lock systems), reservoir bracket,
disposable flow regulator, ringstand, 1/16 i.d. tubing and four-
or eight-into-one micro-manifold.
Valve Choices:
- Pinch
1/32 i.d. silicon tube passes through, and is pinched closed by
the valve. No liquid comes into contact with the valve. Easiest valves
to clean and switch tubing. Open and close in approx. 30-50 ms.
- Teflon
Excellent chemical and corrosion resistance. Non-stick surface resists
particle and chemical deposits. Faster opening and closing in
approx. 10 ms.
The Economy Pinch
Valve System includes ValveLink8 controller, four pinch valves, 35 ml
syringes, 2-way stopcocks, reservoir bracket, ringstand, 1/16 i.d.
tubing and four-into-one micro-manifold.
Computer Interfacing:
Perfusion systems
accept real-time TTL inputs to control valves so they can be controlled
by a computer using most data acquisition hardware and software which
you may already have. An optional program called EasyCode® is available
for the Macintosh and PC/Windows to program ValveBanks (not ValveLinks).
This software is used before an experiment valve sequences are
downloaded into the memory of the ValveBank where they are run.
Four
easy steps to selecting your perfusion system.
Click on option to learn more.
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Number of channels required |
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Valve type |
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Type of controller
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Optional Software |
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Channels
Determines the number of liquids that can be controlled. 4-channel
ValveLink systems actually come with a ValveLink8 controller (we
don't make a ValveLink4), so they can easily be expanded later by
adding more valves. 16-channel ValveBank systems actually come with
two ValveBank8 controllers connected electronically to act as one
unit.
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Valves
and Fittings
Pinch
Valves for Reduced Maintenance
Easiest valves to clean and switch tubing. Liquids never touch the
valves. Switches in 30-50ms. 1/32 i.d. silicone tube passes
through, and is pinched closed by solenoid activation.
Teflon
Valves for Fast Switching
Required for fast kinetics applications. Excellent chemical and
corrosion resistance. Non-stick surface resists particles and chemical
deposits. Switches in less than 10ms, with 20µl of dead volume
from port to port. Threaded female inlet and outlet ports accept
Hose Barb, Luer Lock and Nut & Ferrule fittings (side). All
valves include an individual indicator LED.
Fittings
for your Teflon Valves
Hose Barbs are standard and available for 1/8 & 1/16
i.d. soft tubing. Luer Lock fittings attach directly to syringe
reservoirs for minimal dead volume. Nut & Ferrule fittings are
ideal for drug discovery applications that require hard Teflon tubing.
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Valve
Controllers - ValveLink® and ValveBank®
ValveLinks are less expensive and include manual push buttons, digital/TTL
and serial inputs to control valves. ValveBanks include all of the
above, plus they can be programmed through their keypad and LCD screen
or EasyCode software from a Macintosh or PC-Windows. ValveBanks
run user valve sequence 'programs' without a computer, and include
eight programmable digital outputs for control of external devices.
Entire ValveBank programs can also be triggered by a single TTL pulse.
All controllers include dual serial ports for communicating with multiple
devices on a daisy-chain bus.
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ValveLink®
Controllers
Run experiments automatically even unattended
By running experiments automatically, you are free to accomplish
other tasks saving you both time and money.
Microprocessor-based for accuracy and flexibility
Even our low-cost ValveLink® controller has powerful perfusion
commands and capabilities not offered by competing valve drivers.
Low noise & low voltage valve control
Designed for electrophysiology. CE marked for Europe.
Manual, TTL, and RS-232 inputs
Control manually (by push button) or by computer simultaneously.
These valve controllers are still the only ones with serial ports
thanks to their microprocessor design.
Low cost & low profile, simple design
Optional BNC cables and 19 rack-mounting brackets.
ValveLink controllers switch 12V DC solenoid valves with an accuracy
of 0.01 seconds. Valves are opened or closed rapidly using full
power, then held-in at 1/2 power to prevent thermal transfer to
your solutions. Low noise circuitry minimizes recording artifacts
in electrophysiology. ValveLinks are designed for use with popular
data capture/control software and include dual RS-232 serial ports
for daisy-chaining with other telegraphed instruments. All products
include a one-year limited warranty covering both parts and labor.
ValveLink8 & 16 Controllers
ValveLinks® are less expensive than ValveBanks and include manual
push buttons, digital/TTL and serial inputs to control valves. They
are designed for easy control by your data acquisition software.
The ValveLink16 is the controller of choice for dose response work
at pharmaceutical companies and the NIH.
ValveBank
Controllers
Run experiments automatically even unattended
By running experiments automatically, you are free to accomplish
other tasks saving you both time and money.
Microprocessor-based for accuracy and flexibility
The ValveBank controller has powerful perfusion commands and
capabilities not offered by competing valve drivers.
Low noise & low voltage valve control
Designed for electrophysiology. CE marked for Europe.
Manual, TTL, and RS-232 inputs
Control manually (by push button) or by computer simultaneously.
These valve controllers are still the only ones with serial ports
thanks to their microprocessor design.
Low cost & low profile, simple design
Optional BNC cables and 19 rack-mounting brackets.
ValveBank controllers switch 12V DC solenoid valves with an accuracy
of 0.01 seconds. Valves are opened or closed rapidly using full
power, then held-in at 1/2 power to prevent thermal transfer to
your solutions. Low noise circuitry minimizes recording artifacts
in electrophysiology. ValveBanks are designed for use with popular
data capture/control software and include dual RS-232 serial ports
for daisy-chaining with other telegraphed instruments. All products
include a one-year limited warranty covering both parts and labor.
ValveBank4 & 8 Controllers
Even ten years after its introduction, the ValveBank remains
the only programmable valve controller for physiology that does
not require a computer. ValveBanks include all of the features of
ValveLinks®, plus they can be programmed through their keypad
and LCD screen or EasyCode® software from a Macintosh or PC.
ValveBanks run user valve sequences without a computer and include
eight programmable digital outputs for control of external devices
such as stimulators, pumps and recording devices. Entire ValveBank
programs can even be triggered by a single TTL pulse.
Specifications ValveBank4 & 8
Digital inputs activate valves by computer or external devices
including level sensors, flow meters, and UV/VIS detectors.
1.5 Amp, 12V AC power supply included
User-selectable for normally open or closed valves
Dimensions: 10" x 7.5" x 2" Weight: 5 lbs.
(2.27kg.)
Link multiple ValveBanks with a cable to operate up to 80
channels simultaneously.
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EasyCode
Program your valve and TTL on-off sequences with a Macintosh or PC-Windows
compatible computer using graphic 'click-and-drag' timebars. Save
and load unlimited programs to disk, print out program listings, then
download your programs into the ValveBank's memory in one simple step.
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Copyright©
1999 Scientific Systems Design, Inc.
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